Contributions of B Cell Antigen Presentation to the Pathogenesis of Multiple Sclerosis

Time: 11:30 am
day: Day One


  • Multiple lines of evidence suggest B cells promote autoimmunity within the CNS by functioning as antigen presenting cells
  • Murine models in which B cells coordinate antigen-specific targeting in the CNS provide insights into the immune mechansims of multiple sclerosis
  • The meninges serve as a critical immune tissue in which antigen access and presentation occur