Exploring New Humanized Mice Mounting Class-Switched, Hypermutated & Neutralizing Antibody Responses
Time: 4:00 pm
day: Day Two
Details:
- Explore an advanced next generation humanized mouse model, H-Mice®
- Discover how H-Mice® has been constructed by grafting immunodeficient NSG/ cKitW-41J neonatal mice with freshly isolated human umbilical cord CD34+ hematopoietic stem cells (HSCs) via intracardiac injection, and subsequent potentiation of immune cellular elements differentiation by hormonal conditioning
- Learn how H-Mice® provide a powerful platform for pre-clinical testing of vaccines, modulators of the antibody response and therapeutics for autoimmunity
