Targeted Biologics That Mobilize a Novel Regulatory cd8 T Cell Network to Reduce the Pathology of Human T Cell Driven Autoimmune Disease
Time: 5:00 pm
day: Day Two
Details:
- Review the modulation of a cytolytic regulatory CD8 T cell population that may prevent autoimmune driven inflammatory cascades
- Unveil the prevalence of CD8 Treg and their potential dysfunction across a spectrum of autoimmune disorders
- Discuss the introduction of targeted bispecific molecules that engage regulatory CD8 T cells, causing cytolytic elimination of pathogenic CD4 T cells and reduction of disease severity in aggressive inflammatory models
